HDXperts

HDX MS is routinely utilized to identify the binding site of small molecules to proteins, as well as for the characterization of binding interfaces between protein/protein and protein/peptide complexes.

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The analysis can performed in samples containing almost any kind of biological buffers (e.g TRIS, BIS-TRIS, HEPES), and using 0.2 to 1 mg of protein.

HDX MS can be used for ligand screening by monitoring areas related to the binding site. The LC-MS and data processing are tailored to interrogate a library of compounds to a target protein.

The analysis can performed in samples containing almost any kind of biological buffers (e.g TRIS, BIS-TRIS, HEPES).

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HDXperts provides Chemical Proteomics Services for drug-target identification. Click here for full details